Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924745 | 0.82 | BBOX1 (0.30) | — | |
| SCHEMBL29388164 | 0.82 | BBOX1 (0.30) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL28047635 | 0.81 | MEN1 (0.52) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Trifluoromethanesulfonic Acid SCHEMBL3785097 | 0.79 | MEN1 (0.50) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Trifluoromethanesulfonamide SCHEMBL28047774 | 0.79 | LMNA (0.50) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Trifluoromethanesulfonic Acid SCHEMBL29160398 | 0.79 | CYP3A4 (0.56) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Trifluoromethanesulfonamide SCHEMBL28047636 | 0.79 | LMNA (0.50) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| SCHEMBL31375747 | 0.79 | PSMD14 (0.37) | — | |
| SCHEMBL925224 | 0.78 | DNM1 (0.41) | MEN1LMNAKMT2A | |
| Tetramethylammonium Ion SCHEMBL2940600 | 0.78 | CA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4515024-A1 | METHOD FOR PRODUCING AN IRON NITRIDE COATING ON THE SURFACE OF AN IRON OR IRON ALLOY SUBSTRATE | Brembo S.p.A. (IT) | 2025-03-05 | — | — | EP | claimed |
| WO-2023209585-A1 | METHOD FOR PRODUCING AN IRON NITRIDE COATING ON THE SURFACE OF AN IRON OR IRON ALLOY SUBSTRATE | BREMBO S.P.A. (IT) | 2023-11-02 | — | — | WO | claimed |
| CN-111435705-B | Repairing agent and repairing method thereof and method for preparing photoelectric film | 杭州纤纳光电科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-114570219-A | Pollution-resistant separation membrane with ionic liquid layer on surface and preparation method thereof | 浙江大学 | 2022-06-03 | — | — | CN | claimed |
| US-8772438-B2 | Preparation of polyamides | Invista North America S.är.l. (US) | 2014-07-08 | — | — | US | claimed |
| US-20120264907-A1 | PREPARATION OF POLYAMIDES | INVISTA NORTH AMERICA S.A.R.L. (US) | 2012-10-18 | — | — | US | claimed |
| EP-2451863-A1 | PREPARATION OF POLYAMIDES | Invista Technologies S.A R.L. (CH) | 2012-05-16 | — | — | EP | claimed |
| WO-2011004138-A1 | PREPARATION OF POLYAMIDES | INVISTA TECHNOLOGIES S.A.R.L. (CH) | 2011-01-13 | — | — | WO | claimed |
| US-7442841-B2 | Extraction process | INVISTA NORTH AMERICA S.A R.L. (US) | 2008-10-28 | — | — | US | claimed |
| US-20080051609-A1 | EXTRACTION PROCESS | INVISTA NORTH AMERICA S.A.R.L. (US) | 2008-02-28 | — | — | US | claimed |
| US-20260121095-A1 | Advanced Ion Exchange Membranes And Applications Thereof | WILLIAMS RICHARD KENT (US) | 2026-04-30 | — | — | US | disclosed |
| WO-2025128460-A1 | ADVANCED ION EXCHANGE MEMBRANES AND APPLICATIONS THEREOF | WILLIAMS RICHARD KENT (US) | 2025-06-19 | — | — | WO | disclosed |
| EP-4515024-A1 | METHOD FOR PRODUCING AN IRON NITRIDE COATING ON THE SURFACE OF AN IRON OR IRON ALLOY SUBSTRATE | Brembo S.p.A. (IT) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023209585-A1 | METHOD FOR PRODUCING AN IRON NITRIDE COATING ON THE SURFACE OF AN IRON OR IRON ALLOY SUBSTRATE | BREMBO S.P.A. (IT) | 2023-11-02 | — | — | WO | disclosed |
| CN-114380699-B | Method for synthesizing isophorone diamine, catalyst and preparation method thereof | 山东新和成维生素有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2011004138-A1 | PREPARATION OF POLYAMIDES | INVISTA TECHNOLOGIES S.A.R.L. (CH) | 2011-01-13 | — | — | WO | disclosed |
| EP-2051788-A1 | EXTRACTION PROCESS USING AN IONIC LIQUID | Invista Technologies S.à.r.l. (CH) | 2009-04-29 | — | — | EP | disclosed |
| US-7442841-B2 | Extraction process | INVISTA NORTH AMERICA S.A R.L. (US) | 2008-10-28 | — | — | US | disclosed |
| US-20080051609-A1 | EXTRACTION PROCESS | INVISTA NORTH AMERICA S.A.R.L. (US) | 2008-02-28 | — | — | US | disclosed |
| WO-2008022233-A1 | EXTRACTION PROCESS USING AN IONIC LIQUID | INVISTA TECHNOLOGIES S.A.R.L. (CH) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051609-A1 | EXTRACTION PROCESS | ADH1C, ADH1A, ADH5 | MEN1 3505/4885LMNA 971/4885KMT2A 2389/4885 |
| US-20260121095-A1 | Advanced Ion Exchange Membranes And Applications Thereof | MYOC, MB, MYOF | MEN1 1273/4885LMNA 32/4885KMT2A 4530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.