Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYNJ2 | O15056 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905410 | 0.91 | CYP3A4 (0.47) | SYNJ2MEN1KMT2AMAPTGAA | |
| SCHEMBL7901522 | 0.88 | CYP3A4 (0.65) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| SCHEMBL5707803 | 0.81 | CYP3A4 (0.61) | MEN1KMT2AMAPTGAAHPGD | |
| SCHEMBL28047696 | 0.80 | FFAR1 (0.57) | SYNJ2MEN1KMT2AMAPTGAA | |
| SCHEMBL1937218 | 0.78 | CYP3A4 (0.76) | SYNJ2MEN1KMT2AMAPTGAA | |
| SCHEMBL18677488 | 0.78 | SYNJ2 (0.60) | SYNJ2MEN1KMT2AMAPTGAA | |
| SCHEMBL29757572 | 0.78 | CYP3A4 (0.76) | SYNJ2MEN1KMT2AMAPTGAA | |
| SCHEMBL8894531 | 0.77 | ACHE (0.43) | MEN1KMT2AMAPTGAACYP3A4 | |
| SCHEMBL827858 | 0.77 | CYP3A4 (0.53) | MEN1KMT2AMAPTCYP3A4CYP2D6 | |
| SCHEMBL14925438 | 0.75 | NR1H2 (0.51) | SYNJ2MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405868-A | Treating skin disorders | GOUPIL JEAN-JACQUES (FR) | 1995-04-11 | — | — | US | disclosed |
| US-5360816-A | ORALLY ADMINISTERING 5-METHOXY-PSORALEN TO A PATIENT AND THEN EXPOSING PATIENT TO ULTRAVIOLET RADIATION | GOUPIL JEAN JACQUES (FR) | 1994-11-01 | — | — | US | disclosed |
| US-4429138-A | MULTISTEP, FROM PHLOROGLUCINOL | GOUPIL JEAN JACQUES (FR) | 1984-01-31 | — | — | US | disclosed |