Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 13/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047865 | 0.83 | IDO1 (0.36) | PRKCIFYNCDK8 | |
| SCHEMBL352651 | 0.83 | CYP4F2 (0.40) | PRKCIFYNCDK8 | |
| SCHEMBL4830146 | 0.77 | HSD17B1 (0.58) | FYNCHEK1 | |
| SCHEMBL5668347 | 0.75 | PRKCI (0.50) | PRKCIFYNCDK8ATRCHRNB4 | |
| SCHEMBL6948234 | 0.74 | METAP2 (0.50) | — | |
| SCHEMBL4013546 | 0.74 | IDO1 (0.50) | — | |
| SCHEMBL1031072 | 0.74 | IDO1 (0.50) | — | |
| SCHEMBL4191589 | 0.73 | PRKCI (0.72) | PRKCIFYNCDK8CHRNB4CHRNA3 | |
| SCHEMBL1520375 | 0.72 | RAB9A (0.43) | — | |
| SCHEMBL18297788 | 0.71 | PRKCI (0.76) | PRKCIFYNCDK8CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |