Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28047841 | 0.83 | TYR (0.46) | TYRCYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL28047703 | 0.82 | APLNR (0.51) | ALDH1A1CYP3A4KMT2A | |
| SCHEMBL3639794 | 0.82 | POLB (0.51) | POLBTRIM24TYRTRIM33ESR1 | |
| SCHEMBL20576951 | 0.80 | ERN1 (0.40) | POLBERN1GAAHPGDKDM4E | |
| SCHEMBL17965863 | 0.79 | GAA (0.56) | POLBESR1CYP19A1ESR2GAA | |
| SCHEMBL3625530 | 0.78 | POLB (0.57) | POLBTRIM24TYRTRIM33ESR1 | |
| SCHEMBL28988621 | 0.77 | ALDH1A1 (0.43) | GAAALDH1A1HPGDKMT2A | |
| SCHEMBL28227756 | 0.76 | POLB (0.55) | POLBTRIM24TYRTRIM33ESR1 | |
| SCHEMBL910548 | 0.75 | POLB (0.62) | POLBTRIM24TYRTRIM33ESR1 | |
| SCHEMBL9714559 | 0.74 | TSHR (0.42) | POLBCYP3A4MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |