Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3625530 | 0.83 | POLB (0.57) | POLBESR1CYP19A1ESR2TRIM24 | |
| SCHEMBL584252 | 0.81 | APLNR (0.59) | ALDH1A1 | |
| SCHEMBL3312341 | 0.81 | KMT2A (0.45) | POLBTRIM24TYRTRIM33ERN1 | |
| SCHEMBL1529037 | 0.80 | TYR (0.65) | TYRCYP3A4 | |
| SCHEMBL28034772 | 0.80 | MEN1 (0.42) | POLBTRIM24TYRTRIM33ERN1 | |
| SCHEMBL13690496 | 0.79 | POLB (0.65) | POLBESR1CYP19A1ESR2TYR | |
| SCHEMBL27297772 | 0.79 | POLB (0.65) | POLBESR1CYP19A1ESR2TRIM24 | |
| SCHEMBL2045876 | 0.78 | POLB (0.64) | POLBESR1CYP19A1ESR2TRIM24 | |
| SCHEMBL7332987 | 0.78 | ADRA1A (0.62) | ALDH1A1 | |
| SCHEMBL8621322 | 0.77 | POLB (0.63) | POLBESR1CYP19A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102206245-A | Method for preparing sweetener doubleNeotame and application of sweetener doubleNeotame in field of feeds | ZHIQIANG WANG | 2011-10-05 | — | — | CN | claimed |
| US-8937090-B2 | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO COMPANY, LTD. (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | SHISEIDO COMPANY, LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| CN-102206245-A | Method for preparing sweetener doubleNeotame and application of sweetener doubleNeotame in field of feeds | ZHIQIANG WANG | 2011-10-05 | — | — | CN | disclosed |
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2255780-A1 | PARAKERATOSIS INHIBITOR, PORE SHRINKING AGENT OR AGENT FOR PREVENTING OR IMPROVING ROUGH SKIN, AND COMPOSITION FOR EXTERNAL USE ON THE SKIN CONTAINING THE SAME | Shiseido Company, Ltd. (JP) | 2010-12-01 | — | — | EP | disclosed |
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-1941861-A1 | WRINKLE-IMPROVING AGENT | Shiseido Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1880711-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| US-20050175755-A1 | Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof | AJINOMOTO CO., INC. (JP) | 2005-08-11 | — | — | US | disclosed |
| US-6794531-B2 | ARTIFICIAL SWEETENER | AJINOMOTO CO., INC. (JP) | 2004-09-21 | — | — | US | disclosed |
| US-20040176472-A1 | Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof | AJINOMOTO CO., INC. (JP) | 2004-09-09 | — | — | US | disclosed |
| US-20020133037-A1 | Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof | AJINOMOTO CO. INC (JP) | 2002-09-19 | — | — | US | disclosed |
| EP-1231215-A1 | PROCESS FOR THE PRODUCTION OF ASPARTYLDIPEPTIDE ESTER DERIVATIVES, NOVEL INTERMEDIATES THEREFOR AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | Ajinomoto Co., Inc. (JP) | 2002-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | POLB 1408/4885ESR1 4749/4885CYP19A1 3638/4885 |
| US-20020133037-A1 | Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof | DPP4, DNPEP, IAPP | POLB 2878/4885ESR1 4251/4885CYP19A1 3026/4885 |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | CUTA, AAAS, NUP160 | POLB 1724/4885ESR1 4286/4885CYP19A1 3564/4885 |
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | CUTA, GLRA3, ARGLU1 | POLB 3814/4885ESR1 2169/4885CYP19A1 4273/4885 |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | POLB 882/4885ESR1 4721/4885CYP19A1 3356/4885 |
| US-20040176472-A1 | Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof | DPP4, DNPEP, IAPP | POLB 2878/4885ESR1 4251/4885CYP19A1 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.