Arginine

SCHEMBL28048007

CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	KDM1A	O60341	3/20	0.34

▸	MAOB	P27338	1/20	0.34

▸	KDM5A	P29375	1/20	0.34

▸	KDM1B	Q8NB78	1/20	0.34

▸	APLNR	P35414	4/20	0.33

▸	MC4R	P32245	1/20	0.33

▸	C5AR1	P21730	1/20	0.33

▸	GLP1R	P43220	4/20	0.32

▸	SCTR	P47872	1/20	0.32

▸	GHSR	Q92847	2/20	0.32

▸	TUBB4A	P04350	1/20	0.31

▸	TUBB	P07437	1/20	0.31

▸	TUBA3C	P0DPH7	1/20	0.31

▸	TUBA1B	P68363	1/20	0.31

▸	TUBA4A	P68366	1/20	0.31

▸	TUBB4B	P68371	1/20	0.31

▸	TUBB3	Q13509	1/20	0.31

▸	TUBB2A	Q13885	1/20	0.31

▸	TUBB8	Q3ZCM7	1/20	0.31

▸	TUBA3E	Q6PEY2	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Arginine SCHEMBL21569401	0.92	KDM1A (0.34)	KDM1AMAOBKDM5AKDM1BAPLNR
Arginine SCHEMBL27671351	0.91	TUBB4A (0.32)	C5AR1TUBB4ATUBBTUBA3CTUBA1B
Arginine SCHEMBL23456962	0.90	GLP1R (0.34)	KDM1AMAOBKDM5AKDM1BAPLNR
Arginine SCHEMBL29238661	0.90	APLNR (0.39)	KDM1AMAOBKDM5AKDM1BAPLNR
Arginine SCHEMBL27090217	0.88	TUBB4A (0.36)	KDM1AMAOBKDM5AKDM1BAPLNR
Phenylalanine SCHEMBL1239600	0.88	GHSR (0.35)	APLNRGHSR
Arginine SCHEMBL18042243	0.86	MC4R (0.33)	KDM1AMAOBKDM5AKDM1BAPLNR
Arginine SCHEMBL8073440	0.86	MC4R (0.34)	KDM1AMAOBKDM5AKDM1BAPLNR
Tyrosine SCHEMBL28368653	0.86	TUBB4A (0.40)	KDM1AMAOBKDM5AKDM1BMC4R
Arginine SCHEMBL27447445	0.85	TUBB4A (0.35)	APLNRMC4RC5AR1GHSRTUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-105237626-A	Antimicrobial peptide HJH-3 and application thereof	HENAN INST SCIENCE & TECH	2016-01-13	—	—	CN	disclosed