Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28246139 | 0.83 | MEN1 (0.62) | MEN1KMT2AHTR6MAPTLMNA | |
| SCHEMBL2037678 | 0.82 | MET (0.59) | MEN1KMT2AHTR6MAPTTP53 | |
| SCHEMBL28246137 | 0.82 | FEN1 (0.47) | MEN1KMT2AHTR6FEN1 | |
| SCHEMBL6816146 | 0.79 | HDAC3 (0.50) | MEN1KMT2AHTR6MAPTHDAC3 | |
| SCHEMBL27148809 | 0.79 | SLC22A6 (0.50) | MEN1KMT2AHTR6MAPTTP53 | |
| SCHEMBL25030920 | 0.78 | MEN1 (0.41) | MEN1KMT2AMAPTFEN1TSHR | |
| SCHEMBL7832104 | 0.77 | HTR6 (0.47) | MEN1KMT2AHTR6MAPTTSHR | |
| SCHEMBL28406584 | 0.74 | POLB (0.53) | MEN1KMT2AHTR6MAPTFEN1 | |
| SCHEMBL28405115 | 0.73 | MAPT (0.65) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL1015301 | 0.73 | HTR6 (0.52) | MEN1KMT2AHTR6MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450218-B | As the indoles three also ring derivatives of CRTH2 receptor antagonist | SHANDONG HENRY MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2015-12-23 | — | — | CN | disclosed |