Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520044 | 0.85 | MAPT (0.69) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL28246139 | 0.83 | MEN1 (0.62) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL5784803 | 0.83 | MAPT (0.78) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL2037678 | 0.82 | MET (0.59) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL28406584 | 0.80 | POLB (0.53) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL6109703 | 0.79 | MAPT (0.81) | MAPTTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27148809 | 0.79 | SLC22A6 (0.50) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL945682 | 0.74 | NR3C1 (0.55) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL7083892 | 0.74 | MAPT (0.67) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL28048016 | 0.73 | MEN1 (0.51) | MAPTTP53MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530339-B | Synthetic method of benzenesulfonyl-containing indole compound | 青岛农业大学 | 2020-06-05 | — | — | CN | disclosed |