Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731476 | 0.77 | KDM4E (0.78) | KDM4EALDH1A1GAAHPGDCYP1A2 | |
| SCHEMBL27931300 | 0.76 | ADORA2A (0.56) | TACR3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL28160159 | 0.74 | TACR3 (0.54) | TACR3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL28048083 | 0.74 | LMNA (0.49) | KDM4EALDH1A1GAAHPGDCYP1A2 | |
| SCHEMBL27832687 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1GAAHPGDCYP1A2 | |
| SCHEMBL29114095 | 0.73 | GPR84 (0.38) | KDM4EALDH1A1TSHRADORA3 | |
| SCHEMBL13972063 | 0.73 | TACR3 (0.64) | TACR3ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL5318703 | 0.72 | KDM4E (0.75) | KDM4EALDH1A1GAAHPGDCYP1A2 | |
| SCHEMBL28002147 | 0.72 | KDM4E (0.53) | TACR3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30948991 | 0.71 | TLR8 (0.60) | KDM4EALDH1A1GAAHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175327-A | Synthesis method of quinoline derivatives | UNIV NANYANG NORMAL | 2015-12-23 | — | — | CN | disclosed |