Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364503 | 0.79 | TOP1 (0.44) | LMNATOP1NUDT1ADORA2AKDM4E | |
| SCHEMBL2404468 | 0.78 | DHODH (0.63) | LMNAPDE10ADHODHTSHRPOLB | |
| SCHEMBL971895 | 0.77 | LMNA (0.62) | LMNAESR1ESR2NUDT1ADORA2A | |
| SCHEMBL27909470 | 0.77 | LMNA (0.53) | LMNAESR1ESR2NUDT1ADORA2A | |
| SCHEMBL27810976 | 0.76 | LMNA (0.61) | LMNAESR1ESR2NUDT1ADORA2A | |
| SCHEMBL28239158 | 0.76 | LMNA (0.61) | LMNAESR1ESR2NUDT1ADORA2A | |
| SCHEMBL2404536 | 0.75 | DHODH (0.52) | LMNAPDE10ADHODHTSHRGAA | |
| SCHEMBL28962062 | 0.74 | NUDT1 (0.58) | LMNAESR1ESR2NUDT1ADORA2A | |
| SCHEMBL28048054 | 0.74 | TACR3 (0.48) | NUDT1KDM4EPDE10ATSHRGAA | |
| SCHEMBL13758058 | 0.73 | PDE10A (0.60) | LMNAESR1ESR2TOP1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175327-B | A kind of synthetic method of quinoline | 南阳师范学院 | 2017-07-14 | — | — | CN | disclosed |
| CN-105175327-A | Synthesis method of quinoline derivatives | UNIV NANYANG NORMAL | 2015-12-23 | — | — | CN | disclosed |