Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827660 | 0.76 | PARP1 (0.35) | MEN1ALDH1A1KMT2A | |
| Bromide SCHEMBL7991329 | 0.75 | PARP1 (0.34) | MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9593255 | 0.74 | HDAC3 (0.32) | — | |
| SCHEMBL5072999 | 0.72 | ATM (0.36) | MEN1KMT2A | |
| SCHEMBL5077566 | 0.72 | HDAC3 (0.32) | — | |
| SCHEMBL5081250 | 0.71 | HRH1 (0.37) | MEN1ALDH1A1KMT2A | |
| SCHEMBL4777972 | 0.70 | ADRA2C (0.34) | MEN1ALDH1A1KMT2A | |
| Iodide SCHEMBL7792123 | 0.69 | ADRA2C (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL16268830 | 0.68 | OPRM1 (0.32) | — | |
| SCHEMBL24469636 | 0.64 | PARP1 (0.56) | HTR1APARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263924-A | Cxcr7 receptor modulators | ACTELION PHARMACEUTICALS LTD | 2016-01-20 | — | — | CN | disclosed |