Phosphoric Acid

Phosphoric Acid

SCHEMBL28048543

CC(Cl)CCO.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.38

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
GABBR2 O75899 1/20 0.34
GABBR1 Q9UBS5 1/20 0.34
FDPS P14324 4/20 0.33
METAP1 P53582 1/20 0.32
ANPEP P15144 3/20 0.31
LAP3 P28838 2/20 0.31
ERAP1 Q9NZ08 1/20 0.31
PPARD Q03181 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875091 0.86
SCHEMBL9239025 0.86
Phosphoric Acid SCHEMBL25368636 0.80 TSHR (0.39) ALDH1A1TDP1GABBR2GABBR1FDPS
Phosphoric Acid SCHEMBL6428061 0.80 TSHR (0.39) ALDH1A1TDP1GABBR2GABBR1FDPS
Phosphoric Acid SCHEMBL10861254 0.78 TSHR (0.37) ALDH1A1TDP1GABBR2GABBR1FDPS
3-Methylbutanol SCHEMBL4718917 0.78 ALDH1A1 (0.41) ALDH1A1TDP1GABBR2GABBR1FDPS
Phosphoric Acid SCHEMBL14890175 0.76 CA2 (0.46) ALDH1A1TDP1GABBR2GABBR1FDPS
Phosphoric Acid SCHEMBL28943185 0.76 CA2 (0.46) ALDH1A1TDP1GABBR2GABBR1FDPS
Phosphoric Acid SCHEMBL28671769 0.75 ALDH1A1 (0.42) ALDH1A1TDP1GABBR2GABBR1FDPS
Phosphoric Acid SCHEMBL27897703 0.75 LAP3 (0.43) FDPSMETAP1ANPEPLAP3TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103038931-B Non-aqueous electrolyte secondary battery ADEKA CORP. (JP) 2016-01-20 CN disclosed