Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21798510 | 0.83 | NOTUM (0.50) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL5069267 | 0.81 | ALDH1A1 (0.50) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL8918372 | 0.80 | NOTUM (0.55) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL11848148 | 0.79 | NOTUM (0.46) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL6269619 | 0.78 | NOTUM (0.49) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL11348836 | 0.77 | NOTUM (0.42) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL5364732 | 0.76 | HDAC8 (0.55) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL8922927 | 0.75 | NOTUM (0.50) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL9132803 | 0.74 | ALDH1A1 (0.52) | NOTUMTSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL4688756 | 0.73 | SMN1; SMN2 (0.56) | NOTUMTSHRALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254553-B | The preparation method of Silodosin intermediate | 黄欢 | 2018-04-10 | — | — | CN | disclosed |
| CN-105254553-A | Method for preparing silodosin midbody | HUANG HUAN | 2016-01-20 | — | — | CN | disclosed |