Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | WDR5 | P61964 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030405 | 0.80 | P2RX7 (0.43) | POLBHPGDALDH1A1MAPK1CYP1A2 | |
| SCHEMBL28716532 | 0.74 | WDR5 (0.44) | POLBHPGDWDR5ALDH1A1CYP1A2 | |
| SCHEMBL29493339 | 0.74 | WDR5 (0.44) | POLBHPGDWDR5ALDH1A1CYP1A2 | |
| SCHEMBL6901764 | 0.74 | P2RX7 (0.40) | POLBMAOBNPC1 | |
| SCHEMBL30791568 | 0.73 | PTK2 (0.53) | POLBWDR5MAOBMAPK1NPSR1 | |
| SCHEMBL6480960 | 0.73 | POLB (0.40) | POLBHPGDALDH1A1MAPK1CYP1A2 | |
| SCHEMBL68385 | 0.73 | POLB (0.40) | POLBHPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5565736 | 0.72 | POLB (0.42) | POLBHPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29493360 | 0.71 | ADORA2A (0.49) | — | |
| SCHEMBL6031065 | 0.70 | KMT2A (0.51) | ALDH1A1CYP1A2CYP2C19CYP2C9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933590-B | The trisubstituted silicyl of antifungal N-[() methyl]-carboxamide derivative | BAYER CROPSCIENCE AG (DE) | 2016-05-18 | — | — | CN | disclosed |