Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048853 | 0.87 | NCF1 (0.55) | NCF1ACP1TOP2ASIGMAR1 | |
| SCHEMBL4731923 | 0.86 | NCF1 (0.62) | NCF1GAAKMT2AKDM4EGLA | |
| SCHEMBL19475361 | 0.83 | ACP1 (0.57) | GAAPOLBKDM4ENPC1LMNA | |
| SCHEMBL28227463 | 0.76 | CNR1 (0.59) | GAAPOLBKMT2AKDM4EGLA | |
| SCHEMBL593492 | 0.75 | SIGMAR1 (0.44) | GAAPOLBKMT2AKDM4ELMNA | |
| SCHEMBL4733334 | 0.74 | NCF1 (1.00) | NCF1GAAPOLBKDM4EGLA | |
| SCHEMBL3718831 | 0.73 | SIGMAR1 (0.60) | POLBKMT2AMEN1SIGMAR1 | |
| SCHEMBL6071998 | 0.73 | ALDH1A1 (0.51) | GAAPOLBKMT2AKDM4EGLA | |
| SCHEMBL17433848 | 0.73 | NCF1 (0.57) | NCF1KMT2AKDM4ELMNARAB9A | |
| SCHEMBL17433976 | 0.72 | NCF1 (0.62) | NCF1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377851-A | BET bromodomain inhibitors and therapeutic methods using these inhibitors | UNIV MICHIGAN REGENTS | 2016-03-02 | — | — | CN | disclosed |