Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753264 | 0.89 | LTA4H (0.57) | CYP11B1CYP11B2CHRNB2CHRNA4LTA4H | |
| SCHEMBL27512940 | 0.82 | CHRNB2 (0.54) | CHRNB2CHRNA4NPC1RAB9A | |
| SCHEMBL30150593 | 0.81 | RAB9A (0.62) | CHRNB2CHRNA4RAB9A | |
| SCHEMBL1323646 | 0.81 | RAB9A (0.62) | CHRNB2CHRNA4RAB9A | |
| SCHEMBL1070131 | 0.80 | NPC1 (0.73) | LTA4HNPC1RAB9ATAAR1 | |
| Bromide SCHEMBL27462942 | 0.80 | RAB9A (0.60) | CHRNB2CHRNA4RAB9A | |
| SCHEMBL13097024 | 0.80 | MAPK1 (0.64) | — | |
| Pyridine SCHEMBL5787948 | 0.79 | RAB9A (0.59) | CHRNB2CHRNA4RAB9A | |
| SCHEMBL7536878 | 0.79 | CHRNB2 (0.57) | CYP11B1CYP11B2CHRNB2CHRNA4LTA4H | |
| SCHEMBL5681576 | 0.78 | RAB9A (0.54) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189515-A | Furopyridines as bromodomain inhibitors | GLAXOSMITHKLINE IP NO 2 LTD | 2015-12-23 | — | — | CN | disclosed |