Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.57 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.56 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.56 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.56 |
| ▸ | TLR2 | O60603 | 3/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL27910098 | 1.00 | LPAR1 (0.64) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL1333581 | 0.89 | LPAR1 (0.69) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Monoethanolamine SCHEMBL27549117 | 0.88 | LPAR3 (0.84) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Monoethanolamine SCHEMBL27411197 | 0.88 | LPAR3 (0.84) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Glycerin SCHEMBL28048922 | 0.87 | LPAR1 (0.64) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Monoethanolamine SCHEMBL27635540 | 0.86 | LPAR3 (0.81) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Choline SCHEMBL28271776 | 0.86 | LPAR1 (0.60) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Choline SCHEMBL28104751 | 0.86 | LPAR1 (0.60) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Choline SCHEMBL28147311 | 0.86 | LPAR1 (0.60) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Serine SCHEMBL28049071 | 0.84 | LPAR1 (0.57) | LPAR1LPAR3LPAR2LPAR5LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103179951-B | Phospholipid depot | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-01-20 | — | — | CN | disclosed |