Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049141 | 0.88 | PTGS2 (0.45) | GAAL3MBTL1PTGS2PTGS1PRKCZ | |
| SCHEMBL28049063 | 0.87 | FFAR4 (0.40) | GAAL3MBTL1PTGS2FFAR4PTGS1 | |
| SCHEMBL28123376 | 0.86 | PTGS2 (0.40) | GAAL3MBTL1PTGS2PTPN1PTGS1 | |
| SCHEMBL28358513 | 0.81 | PTGS2 (0.38) | GAAL3MBTL1PTGS2FFAR4PTPN1 | |
| SCHEMBL28354792 | 0.79 | CYP2A6 (0.41) | PTGS2PTPN1PTGS1EGFR | |
| SCHEMBL16048887 | 0.78 | PRKCZ (0.45) | LMNAPTGS2PTGS1CA12CA2 | |
| SCHEMBL28049131 | 0.77 | FFAR4 (0.48) | PTGS2FFAR4PTGS1ALPISMN1; SMN2 | |
| SCHEMBL28354819 | 0.76 | RAB9A (0.42) | PTGS2FFAR4PTGS1NPC1RAB9A | |
| SCHEMBL16048662 | 0.75 | FFAR4 (0.39) | LMNAGAAL3MBTL1PTGS2FFAR4 | |
| SCHEMBL28123342 | 0.73 | FFAR4 (0.37) | L3MBTL1PTGS2FFAR4ALPIPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209446-A | GPR120 agonists for the treatment of type ii diabetes | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |