Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049141 | 0.88 | PTGS2 (0.45) | PRKCZPTGS2GAAL3MBTL1PTGS1 | |
| SCHEMBL28049099 | 0.87 | LMNA (0.35) | FFAR4PRKCZPTGS2KDM4EALDH1A1 | |
| SCHEMBL28123376 | 0.86 | PTGS2 (0.40) | PTGS2KDM4EALDH1A1MEN1MAPT | |
| SCHEMBL28123342 | 0.83 | FFAR4 (0.37) | FFAR4PRKCZPTGS2L3MBTL1PTGDR2 | |
| SCHEMBL28358513 | 0.81 | PTGS2 (0.38) | FFAR4PTGS2POLBGAAL3MBTL1 | |
| SCHEMBL28049060 | 0.79 | FFAR4 (0.43) | FFAR4PRKCZANO1KDM4EMAPT | |
| SCHEMBL28354792 | 0.79 | CYP2A6 (0.41) | PTGS2PTGS1 | |
| SCHEMBL16048887 | 0.78 | PRKCZ (0.45) | PRKCZPTGS2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28122721 | 0.77 | FFAR4 (0.45) | FFAR4MEN1POLBMAPTXBP1 | |
| SCHEMBL28354819 | 0.76 | RAB9A (0.42) | FFAR4PTGS2KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414434-A | Isothiazole derivatives as gpr120 agonists for the treatment of type ii diabetes | 詹森药业有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-105209446-A | GPR120 agonists for the treatment of type ii diabetes | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |