Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186176 | 0.84 | HDAC1 (0.42) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL24786404 | 0.80 | LMNA (0.50) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL29225190 | 0.80 | KMT2A (0.45) | HDAC1HDAC6TSHRADRA1AHSP90AA1 | |
| SCHEMBL10588692 | 0.79 | HDAC1 (0.42) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL27337562 | 0.79 | ALDH1A1 (0.50) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL21612934 | 0.78 | ALDH1A1 (0.45) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL25405562 | 0.78 | ALDH1A1 (0.45) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL10610539 | 0.76 | ALDH1A1 (0.47) | ALDH1A1F2GLAHPGDLMNA | |
| SCHEMBL27503300 | 0.75 | THRB (0.40) | HDAC1HDAC6HSP90AA1SMN1; SMN2FLT3 | |
| SCHEMBL27794951 | 0.75 | ALDH1A1 (0.42) | ALDH1A1F2GLAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254634-A | SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | BAYER PHARMACEUTICALS CORP | 2016-01-20 | — | — | CN | disclosed |