Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825720 | 0.84 | NTRK1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL19086549 | 0.82 | RAB9A (0.51) | GAAMMP13NPY5RALDH1A1MEN1 | |
| SCHEMBL17578575 | 0.78 | HIF1A (0.63) | MEN1KMT2AL3MBTL1RAB9ANPC1 | |
| SCHEMBL7989247 | 0.77 | MEN1 (0.47) | GAAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4729139 | 0.77 | NPY5R (0.64) | NPY5RALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6581634 | 0.75 | ALDH1A1 (0.54) | GAAALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL6578990 | 0.75 | ALDH1A1 (0.64) | GAAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7977901 | 0.72 | ALDH1A1 (0.52) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9317114 | 0.71 | NTRK1 (0.73) | GAAMMP13NPY5RALDH1A1MEN1 | |
| SCHEMBL6578834 | 0.70 | KDM4E (0.52) | GAAALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384687-A | Quinolinone compound and application thereof in drugs | GUANGDONG HEC PHARMACEUTICAL | 2016-03-09 | — | — | CN | disclosed |