Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28050771 | 0.85 | MEN1 (0.46) | KIF11MEN1KMT2APARP1KDM4E | |
| SCHEMBL23369904 | 0.80 | KIF11 (0.82) | KIF11RXFP1MEN1KMT2APARP1 | |
| SCHEMBL18901313 | 0.77 | KIF11 (0.49) | KIF11RXFP1GABRPGABRDGABRA1 | |
| SCHEMBL29623038 | 0.77 | ALDH1A1 (0.48) | KIF11MEN1KMT2APARP1KDM4E | |
| SCHEMBL26367026 | 0.77 | ALDH1A1 (0.48) | KIF11MEN1KMT2APARP1KDM4E | |
| SCHEMBL28703237 | 0.74 | GPR17 (0.43) | MEN1KMT2AKDM4E | |
| SCHEMBL29507649 | 0.74 | GPR17 (0.43) | MEN1KMT2AKDM4E | |
| SCHEMBL4256780 | 0.74 | KIF11 (0.78) | KIF11RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL29518339 | 0.74 | KIF11 (0.78) | KIF11RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL15985686 | 0.74 | KIF11 (0.55) | KIF11RXFP1KDM4EGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272903-A | Series of fluorine-containing carbazole compounds and preparation method and application thereof | UNIV JIANGSU NORMAL | 2016-01-27 | — | — | CN | disclosed |