SCHEMBL28703237

SCHEMBL28703237

Fc1cc(F)c2c(c1)[nH]c1cc(F)cc(F)c12

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 3/20 0.43
KDM4E B2RXH2 1/20 0.34
DAO P14920 1/20 0.32
TGM2 P21980 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
AHR P35869 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29507649 1.00 GPR17 (0.43) GPR17KDM4EDAOTGM2CES2
SCHEMBL28050771 0.80 MEN1 (0.46) KDM4EDAOMEN1KMT2AGPR84
SCHEMBL26367026 0.79 ALDH1A1 (0.48) KDM4EMEN1KMT2AAHR
SCHEMBL31219143 0.79 KDM4E (0.47) KDM4EAHR
SCHEMBL29623038 0.79 ALDH1A1 (0.48) KDM4EMEN1KMT2AAHR
SCHEMBL29909606 0.75 GPR17 (0.40) GPR17KDM4EKMT2A
SCHEMBL28050860 0.74 KIF11 (0.56) KDM4EMEN1KMT2A
SCHEMBL31219018 0.73 ADORA3 (0.50)
SCHEMBL31219097 0.73 MAPK14 (0.40) GPR17
SCHEMBL25723813 0.73 MEN1 (0.37) GPR17MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163379-A Fluorocarbazolyl diphenylethylene biphenyl compound and preparation method and application thereof 闽都创新实验室 2022-03-11 CN disclosed