Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051089 | 0.98 | ALDH1A1 (0.53) | ALDH1A1TSHRPOLBMAPTGAA | |
| SCHEMBL28050932 | 0.96 | ALDH1A1 (0.51) | ALDH1A1TSHRPOLBMAPTGAA | |
| SCHEMBL28581028 | 0.81 | NR3C1 (0.41) | ALDH1A1TSHRPOLBMAPTGAA | |
| SCHEMBL5186762 | 0.80 | PTGS1 (0.62) | ALDH1A1TSHRPOLBCASP1CASP7 | |
| SCHEMBL10956769 | 0.80 | LIPG (0.50) | THRB | |
| SCHEMBL6684548 | 0.79 | TSHR (0.42) | TSHRMAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL12500471 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TSHRPOLBMAPTGAA | |
| Sulfuric Acid SCHEMBL20984766 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TSHRPOLBMAPTGAA | |
| SCHEMBL27182544 | 0.77 | POLB (0.55) | ALDH1A1TSHRPOLBMAPTGAA | |
| SCHEMBL5130307 | 0.77 | GABRA1 (0.41) | ALDH1A1TSHRPOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109925312-A | For treating the composition, preparation and method of eye disease | 爱尔皮奥治疗有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-105307498-B | Compositions, formulations and methods for treating ocular diseases | 爱尔皮奥治疗有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105307498-A | Compositions, formulations and methods for treating ocular diseases | AERPIO THERAPEUTICS INC | 2016-02-03 | — | — | CN | disclosed |