Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | IDH2 | P48735 | 2/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | CTSC | P53634 | 4/20 | 0.51 |
| ▸ | FADS1 | O60427 | 1/20 | 0.51 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051330 | 0.86 | ADORA3 (0.59) | KDM4EAPPSYKTNNI3KKCNH3 | |
| SCHEMBL3206970 | 0.85 | AURKA (0.70) | SYKAURKACDK1 | |
| SCHEMBL28037898 | 0.84 | KCNH2 (0.54) | KDM4EIDH2SYKCDK1KCNH3 | |
| Trifluoromethylbenzene SCHEMBL28051437 | 0.84 | KDM4E (0.75) | KDM4EIDH2SYKCTSCAURKA | |
| SCHEMBL6033558 | 0.80 | APP (0.48) | KDM4EAPPSYKCTSCKCNH3 | |
| SCHEMBL28051328 | 0.78 | TRPV1 (0.58) | KDM4ECTSCAURKACDC7CDK1 | |
| SCHEMBL4947229 | 0.78 | SYK (0.56) | SYKFADS1TNNI3KCDK1 | |
| SCHEMBL6583848 | 0.77 | CAMK2D (0.64) | SYKFADS1CDK1 | |
| SCHEMBL2946515 | 0.77 | PLK1 (0.77) | SYK | |
| SCHEMBL28051498 | 0.77 | IDH2 (0.53) | KDM4EIDH2SYKTNNI3KCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294588-A | Fluorotriazine-containing derivative, and preparation method and use thereof | WUHAN INST TECHNOLOGY | 2016-02-03 | — | — | CN | disclosed |