Phenylphosphonic Acid

Phenylphosphonic Acid

SCHEMBL28051547

C=CC(=O)OC(C)CN=C=O.O=P(O)(O)c1ccccc1

nearest known ligand 0.39

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
TSHR P16473 2/20 0.35
ALOX15 P16050 1/20 0.35
ALDH1A1 P00352 3/20 0.34
THRB P10828 2/20 0.33
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
THRA P10827 1/20 0.31
CFTR P13569 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
ASF1A Q9Y294 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL27981627 0.86 TSHR (0.36) TSHRALDH1A1
Phthalic Acid SCHEMBL28015772 0.85 ALDH1A1 (0.40) ALOX15ALDH1A1THRBTHRA
SCHEMBL2830959 0.83 TSHR (0.40) TSHRALDH1A1THRB
Maleic Acid SCHEMBL27997600 0.79 HCAR2 (0.40) TSHRALDH1A1HCAR2
Succinic Acid SCHEMBL28005011 0.79 TSHR (0.35) TSHRALDH1A1
SCHEMBL28182877 0.79 TSHR (0.37) TSHRALDH1A1
Methacrylic Acid SCHEMBL28013263 0.78 TSHR (0.34) TSHR
SCHEMBL28015770 0.72 TAAR1 (0.32) TSHR
SCHEMBL1850146 0.71 TSHR (0.38) TSHRALDH1A1SMN1; SMN2
SCHEMBL11580478 0.70 HCAR2 (0.39) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103068411-B Emophysematous therapeutic agent TERUMO CORP. (JP) 2016-01-20 CN disclosed