SCHEMBL28051608

SCHEMBL28051608

CCOC(=O)c1cccc(N)c1NCc1ccc(-c2ccccc2C(N)=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 1/20 0.49
CDC25B P30305 2/20 0.44
AGTR1 P30556 7/20 0.44
AGTR2 P50052 7/20 0.44
LTB4R2 Q9NPC1 1/20 0.42
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
BCAT2 O15382 1/20 0.41
BDKRB1 P46663 4/20 0.41
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7012588 0.90 BDKRB1 (0.47) ALDH1A1HSD17B10LTB4R2BCAT2BDKRB1
SCHEMBL3982628 0.86 ALDH1A1 (0.48) ALDH1A1HSD17B10CDC25BAGTR1AGTR2
SCHEMBL30660078 0.86 ALDH1A1 (0.48) ALDH1A1HSD17B10CDC25BAGTR1AGTR2
SCHEMBL3976380 0.84 SLC6A3 (0.52) ALDH1A1HSD17B10LTB4R2BDKRB1
SCHEMBL7019801 0.81 BDKRB1 (0.42) ALDH1A1HSD17B10AGTR1AGTR2LTB4R2
SCHEMBL9586451 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10CDC25BAGTR1AGTR2
SCHEMBL27334697 0.78 ALDH1A1 (0.49) ALDH1A1HSD17B10CDC25BRAB9ANPSR1
SCHEMBL9587439 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10CDC25BAGTR1AGTR2
SCHEMBL9587150 0.77 ALDH1A1 (0.40) ALDH1A1HSD17B10CDC25BAGTR1AGTR2
SCHEMBL9588421 0.77 ALDH1A1 (0.40) ALDH1A1HSD17B10CDC25BAGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105254526-A Azilsartan process impurity (F) synthesis method CHENGDU ORGANIC CHEMICALS CO 2016-01-20 CN disclosed