Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856667 | 0.89 | MAPT (0.42) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL31257816 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAGHSRKMT2A | |
| SCHEMBL5188507 | 0.84 | MAPT (0.38) | ALDH1A1MAPTLMNATACR1KMT2A | |
| SCHEMBL30165832 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNA | |
| SCHEMBL30910354 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAGHSRTACR1 | |
| SCHEMBL30502301 | 0.80 | HTR2C (0.44) | LMNATACR1 | |
| SCHEMBL31437059 | 0.80 | PARP1 (0.38) | ALDH1A1MAPTLMNATACR1KMT2A | |
| SCHEMBL8147630 | 0.80 | MAPT (0.43) | ALDH1A1MAPTLMNA | |
| SCHEMBL28052467 | 0.79 | TACR1 (0.40) | LMNATACR1 | |
| SCHEMBL6630997 | 0.78 | HTR2C (0.39) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |