SCHEMBL28052644

SCHEMBL28052644

NC(=O)Nc1cccnc1.NC(=O)c1ccccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATG4B Q9Y4P1 1/20 0.61
TSHR P16473 1/20 0.56
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
PKM P14618 1/20 0.53
CDK5 Q00535 1/20 0.52
CDK5R1 Q15078 1/20 0.52
NAMPT P43490 2/20 0.50
PRKCI P41743 1/20 0.48
LMNA P02545 2/20 0.48
HIF1A Q16665 1/20 0.48
NOTUM Q6P988 2/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
CYP11B2 P19099 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29655934 0.84 RAB9A (0.65) RAB9ANPC1PKMNAMPTPRKCI
SCHEMBL162008 0.84 RAB9A (0.65) RAB9ANPC1PKMNAMPTPRKCI
SCHEMBL12469188 0.83 ATG4B (0.69) ATG4BTSHRRAB9ANPC1PKM
Hydrochloric Acid SCHEMBL27677130 0.83 RAB9A (0.62) RAB9ANPC1PKMNAMPTPRKCI
Boric Acid SCHEMBL29121086 0.80 RAB9A (0.59) RAB9ANPC1PKMNAMPTPRKCI
Niacinamide SCHEMBL9065096 0.79 F7 (0.71) TSHRRAB9ANPC1PKMCDK5
Pyridine SCHEMBL28700791 0.78 LMNA (0.61) TSHRRAB9ANPC1PKMCDK5
SCHEMBL61183 0.78
SCHEMBL1505348 0.78
SCHEMBL4914089 0.78 CES2 (0.67) TSHRRAB9ANPC1PKMCDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103635088-B Meter Ge La Statins (Migrastatins) and its purposes 索隆-基特林癌症研究协会 2016-06-15 CN disclosed