SCHEMBL2978320

SCHEMBL2978320

Oc1ccc(O)c(C(O)CCc2ccccc2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.44
ALOX5 P09917 2/20 0.42
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
OPRK1 P41145 2/20 0.42
ADRB2 P07550 2/20 0.41
LMNA P02545 1/20 0.41
ADRB1 P08588 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2A P28223 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41
HTR2B P41595 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2970155 0.87 TYR (0.47) DPP4ALOX5OPRK1ADRB2LMNA
SCHEMBL1837302 0.82 POLB (0.50) TSHRCYP2C19
SCHEMBL7055513 0.79 KEAP1 (0.47) DPP4OPRK1ADRB2KDM4E
SCHEMBL7809649 0.78 ABCB1 (0.54) CYP2C19
SCHEMBL11249677 0.76 IGF1R (0.46) ALOX5IGF1RALOX15OPRK1ADRB2
SCHEMBL9460360 0.75 ADRA1A (0.56) DPP4ALOX15OPRK1ADRB2LMNA
SCHEMBL9150470 0.75 ADRA2A (0.38) ALOX15ADRB2LMNAADRB1ADRA2A
SCHEMBL11251540 0.75 IGF1R (0.49) IGF1RALOX15OPRK1OPRM1KDM4E
SCHEMBL2987540 0.75 ABCB1 (0.43) CYP2C19
SCHEMBL499451 0.75 HIF1A (0.51) OPRK1ADRB2LMNAADRB1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US claimed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 DPP4 988/4885ALOX5 63/4885IGF1R 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.