SCHEMBL28052889

SCHEMBL28052889

C=Cc1ccc(C(=O)O)c(OC(=O)C(=C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
HSD17B10 Q99714 5/20 0.42
HPGD P15428 4/20 0.42
ALDH1A1 P00352 3/20 0.42
USP2 O75604 1/20 0.42
CYP2C19 P33261 1/20 0.42
TRPA1 O75762 1/20 0.41
MCL1 Q07820 2/20 0.41
ESR1 P03372 2/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
HMGB1 P09429 1/20 0.39
TSHR P16473 1/20 0.39
GGT1 P19440 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
BLM P54132 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ELANE P08246 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4863909 0.80 KDM4E (0.53) KDM4EHSD17B10HPGDALDH1A1USP2
SCHEMBL14339914 0.78 KDM4E (0.49) KDM4EHSD17B10HPGDALDH1A1USP2
SCHEMBL3800839 0.78 ALDH1A1 (0.63) KDM4EHSD17B10HPGDALDH1A1USP2
SCHEMBL9778084 0.77 TRPA1 (0.39) KDM4EHPGDALDH1A1TRPA1ELANE
SCHEMBL8440044 0.76 KDM4E (0.77) KDM4EHSD17B10HPGDALDH1A1USP2
SCHEMBL65777 0.75 CFD (0.44) KDM4EHSD17B10HPGDALDH1A1USP2
SCHEMBL14321474 0.74 APP (0.43) KDM4EHSD17B10HPGDALDH1A1USP2
SCHEMBL9607826 0.74 ELANE (0.45) KDM4EALDH1A1CYP2C19TRPA1TDP1
SCHEMBL16966572 0.74 KDM4E (0.70) KDM4EHSD17B10HPGDALDH1A1USP2
SCHEMBL344654 0.74 KDM4E (0.70) KDM4EHSD17B10HPGDALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105339438-B Dye multimer, coloring composition, cured film, color filter and manufacturing method thereof, solid-state imaging element, and image display device 富士胶片株式会社 2018-03-16 CN disclosed
CN-105339438-A Dye multimer, coloring composition, cured film, color filter, method for producing color filter, solid-state imaging element, and image display device FUJIFILM CORP 2016-02-17 CN disclosed