Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.83 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.83 |
| ▸ | ALDH2 | P05091 | 5/20 | 0.83 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.72 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597560 | 0.92 | ACHE (0.86) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL5659265 | 0.91 | ALDH1A1 (1.00) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL28053364 | 0.88 | ACHE (1.00) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL30937985 | 0.87 | ACHE (0.77) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL28464687 | 0.85 | ACHE (0.73) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL5430888 | 0.84 | CHRM1 (1.00) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL30391378 | 0.84 | CHRM1 (1.00) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL22589198 | 0.83 | ALDH3A1 (1.00) | ACHEALDH1A1ALDH3A1ALDH2 | |
| SCHEMBL28469805 | 0.83 | ACHE (0.70) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL22589371 | 0.82 | ALDH3A1 (1.00) | ACHEALDH1A1ALDH3A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237521-B | A kind of cumarin-isatin type compound and its preparation method and purposes | 诸暨市志缇生物科技有限公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105237521-A | Coumarin-isatin type compounds, and preparation method and purpose thereof | UNIV JISHOU | 2016-01-13 | — | — | CN | disclosed |