Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.66 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.65 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329852 | 0.91 | ACHE (0.83) | ACHEHSP90AA1TP53MAPTALDH1A1 | |
| SCHEMBL28053294 | 0.88 | ACHE (1.00) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL4597228 | 0.87 | ACHE (0.77) | ACHEHSP90AA1TP53MAPTALDH1A1 | |
| SCHEMBL22410741 | 0.86 | ACHE (0.75) | ACHEHSP90AA1TP53MAPTALDH1A1 | |
| SCHEMBL14047967 | 0.86 | ACHE (0.75) | ACHEHSP90AA1TP53MAPTALDH1A1 | |
| SCHEMBL578250 | 0.85 | ACHE (0.74) | ACHEHSP90AA1TP53MAPTALDH1A1 | |
| SCHEMBL28053291 | 0.85 | ACHE (0.74) | ACHEHSP90AA1TP53MAPTALDH1A1 | |
| SCHEMBL4597560 | 0.81 | ACHE (0.86) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL5659265 | 0.79 | ALDH1A1 (1.00) | ACHEALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL2056299 | 0.79 | CHRM5 (0.81) | ACHEHSP90AA1TP53MAPTCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237521-B | A kind of cumarin-isatin type compound and its preparation method and purposes | 诸暨市志缇生物科技有限公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105541808-A | Metronidazole-isatin type compound as well as preparation method and application thereof | UNIV JISHOU | 2016-05-04 | — | — | CN | disclosed |
| CN-105237521-A | Coumarin-isatin type compounds, and preparation method and purpose thereof | UNIV JISHOU | 2016-01-13 | — | — | CN | disclosed |