Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | S100A9 | P06702 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053246 | 0.77 | GCK (0.34) | CA1CA2ALOX5APFEN1PLAU | |
| SCHEMBL28053345 | 0.68 | APLNR (0.50) | PTGS1PTGS2CA1CA2S100A9 | |
| SCHEMBL28053340 | 0.63 | PTGS1 (0.42) | PTGS1PTGS2CA1CA2S100A9 | |
| SCHEMBL6619882 | 0.62 | CA1 (0.44) | PTGS1PTGS2CA1CA2 | |
| SCHEMBL21931144 | 0.62 | LMNA (0.38) | CA1CA2S100A9PLAU | |
| SCHEMBL10178016 | 0.61 | CA1 (0.43) | PTGS1PTGS2CA1CA2 | |
| SCHEMBL31028780 | 0.61 | CA1 (0.43) | PTGS1PTGS2CA1CA2ALOX5AP | |
| SCHEMBL454507 | 0.60 | — | — | |
| SCHEMBL6069906 | 0.60 | PTGS2 (0.63) | PTGS1PTGS2 | |
| SCHEMBL16235676 | 0.59 | S100A9 (0.55) | S100A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | claimed |
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |