Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266895 | 0.84 | CYP2C9 (0.44) | TP53LMNAALDH1A1NPC1HTT | |
| SCHEMBL27678180 | 0.80 | OXTR (0.44) | TP53LMNAALDH1A1NPC1HTT | |
| SCHEMBL27676108 | 0.80 | SOAT2 (0.52) | TP53LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL27742973 | 0.80 | KDM4E (0.39) | TP53LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL28784326 | 0.78 | SOAT2 (0.41) | TP53LMNAALDH1A1NPC1HTT | |
| SCHEMBL15716523 | 0.78 | CYP1A2 (0.49) | TP53LMNAALDH1A1NPC1HTT | |
| SCHEMBL4437551 | 0.77 | EIF2AK4 (0.42) | TP53ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL27463663 | 0.77 | CYP1A2 (0.34) | TP53LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL27707912 | 0.77 | HPGD (0.55) | TP53LMNAALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL27728421 | 0.76 | TLR7 (0.41) | TP53LMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377847-A | Kinase inhibitors | CHIESI FARM SPA | 2016-03-02 | — | — | CN | disclosed |