Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.56 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.51 |
| ▸ | CKS1B | P61024 | 3/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CCR9 | P51686 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053260 | 0.80 | ACLY (0.51) | KMT2AGAAMEN1ALDH1A1HPGD | |
| SCHEMBL13510412 | 0.79 | EP300 (0.64) | SLC40A1GLO1CKS1BSKP2SNCA | |
| SCHEMBL16235193 | 0.78 | S100A9 (0.48) | — | |
| SCHEMBL16235471 | 0.78 | KDM4E (0.65) | KMT2AGAAMEN1ALDH1A1HPGD | |
| SCHEMBL16235391 | 0.78 | S100A9 (0.57) | CCR9KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL16235521 | 0.77 | SLC40A1 (0.50) | SLC40A1CCR9KMT2AGAAMEN1 | |
| SCHEMBL16235055 | 0.76 | ALDH1A1 (0.47) | KMT2AGAAMEN1ALDH1A1HPGD | |
| SCHEMBL16235652 | 0.75 | SLC40A1 (0.55) | SLC40A1KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL16235541 | 0.74 | ADAMTS4 (0.52) | GAAALDH1A1 | |
| SCHEMBL16234936 | 0.73 | ALDH1A1 (0.45) | KMT2AGAAMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |