Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16446230 | 0.84 | PROKR1 (0.64) | MEN1KMT2APDE2ASCD5L3MBTL1 | |
| SCHEMBL28853754 | 0.81 | DRD3 (0.50) | ALDH1A1TPSAB1 | |
| SCHEMBL28189351 | 0.80 | PROKR1 (0.50) | ALDH1A1PROKR1CYP3A4TPSAB1 | |
| SCHEMBL28053449 | 0.79 | PROKR1 (0.75) | PROKR1 | |
| Ammonia Solution, Strong SCHEMBL28053450 | 0.79 | PROKR1 (0.49) | ALDH1A1PROKR1CYP3A4TPSAB1 | |
| SCHEMBL28189333 | 0.78 | BTK (0.44) | ALDH1A1F10 | |
| SCHEMBL4036337 | 0.76 | BCL9 (0.61) | MEN1KMT2APROKR1 | |
| SCHEMBL28853756 | 0.74 | DRD2 (0.48) | TPSAB1 | |
| SCHEMBL13570456 | 0.73 | F10 (0.45) | F10CYP3A4TPSAB1 | |
| SCHEMBL8350555 | 0.73 | SCD5 (0.53) | MEN1KMT2APDE2ASCD5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452233-A | Piperidine and azepane derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICALS CO | 2016-03-30 | — | — | CN | claimed |
| CN-105452233-A | Piperidine and azepane derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICALS CO | 2016-03-30 | — | — | CN | disclosed |