Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | DRD3 | P35462 | 8/20 | 0.48 |
| ▸ | DRD1 | P21728 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 4/20 | 0.48 |
| ▸ | DRD5 | P21918 | 4/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28853754 | 0.81 | DRD3 (0.50) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL14323106 | 0.79 | DRD2 (0.54) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL23009630 | 0.79 | SCD5 (0.46) | DRD2DRD3DRD1DRD4DRD5 | |
| Formic Acid SCHEMBL27536013 | 0.79 | TPSAB1 (0.45) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL16368536 | 0.77 | HDAC4 (0.47) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL30531117 | 0.77 | PRMT6 (0.44) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL25359641 | 0.77 | PRMT6 (0.44) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8287053 | 0.76 | KMO (0.49) | DRD2DRD3DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL15922780 | 0.76 | TPSAB1 (0.43) | DRD2DRD3DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL16343416 | 0.76 | HDAC4 (0.46) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452233-B | Piperidine and azepane derivatives as prokineticin receptor modulators | 武田药品工业株式会社 | 2017-12-08 | — | — | CN | claimed |
| CN-105452233-B | Piperidine and azepane derivatives as prokineticin receptor modulators | 武田药品工业株式会社 | 2017-12-08 | — | — | CN | disclosed |