Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053546 | 0.81 | MEN1 (0.50) | TPSAB1ALDH1A1 | |
| SCHEMBL28853756 | 0.81 | DRD2 (0.48) | DRD3DRD2TPSAB1DRD1DRD4 | |
| SCHEMBL28189351 | 0.78 | PROKR1 (0.50) | TPSAB1ALDH1A1 | |
| SCHEMBL4405378 | 0.78 | TPSAB1 (0.58) | TPSAB1 | |
| SCHEMBL27878990 | 0.78 | ALDH1A1 (0.62) | DRD3DRD2ALDH1A1DRD1DRD4 | |
| Ammonia Solution, Strong SCHEMBL28053450 | 0.78 | PROKR1 (0.49) | TPSAB1ALDH1A1 | |
| SCHEMBL25359641 | 0.77 | PRMT6 (0.44) | DRD3DRD2TPSAB1DRD1DRD4 | |
| SCHEMBL16368536 | 0.77 | HDAC4 (0.47) | DRD3DRD2TPSAB1DRD1DRD4 | |
| SCHEMBL30531117 | 0.77 | PRMT6 (0.44) | DRD3DRD2TPSAB1DRD1DRD4 | |
| SCHEMBL13830735 | 0.77 | TPSAB1 (0.60) | TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452233-B | Piperidine and azepane derivatives as prokineticin receptor modulators | 武田药品工业株式会社 | 2017-12-08 | — | — | CN | claimed |
| CN-105452233-B | Piperidine and azepane derivatives as prokineticin receptor modulators | 武田药品工业株式会社 | 2017-12-08 | — | — | CN | disclosed |