Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053635 | 0.89 | MMP1 (0.46) | MAPTMMP1MMP2MMP9HDAC11 | |
| SCHEMBL28640947 | 0.75 | PSMB8 (0.41) | MAPTHDAC11ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL28630349 | 0.75 | PSMB8 (0.41) | MAPTHDAC11ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL28261787 | 0.75 | PSMB8 (0.41) | MAPTHDAC11ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL28053558 | 0.75 | HDAC11 (0.56) | MMP1MMP2MMP9HDAC11LMNA | |
| SCHEMBL28053632 | 0.74 | MEN1 (0.58) | MAPTMMP1MMP2MMP9EGFR | |
| SCHEMBL28624764 | 0.73 | HDAC11 (0.41) | MAPTHDAC11ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL28624872 | 0.73 | HDAC11 (0.41) | MAPTHDAC11ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL28261746 | 0.73 | HDAC11 (0.41) | MAPTHDAC11ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL28053627 | 0.73 | MAPT (0.43) | MAPTHDAC11EGFRHTTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272928-A | Alkenyl amide triazole compound and synthetic method thereof | UNIV SHAANXI NORMAL | 2016-01-27 | — | — | CN | disclosed |