SCHEMBL28053711

SCHEMBL28053711

C=CCOC(=O)C(C(=O)O)C(CC(C)c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.40
ALDH1A1 P00352 4/20 0.39
TRPA1 O75762 4/20 0.39
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PKM P14618 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PDPK1 O15530 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
CASP1 P29466 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28053811 0.88 CYP3A4 (0.40) CYP3A4CYP2C19ALDH1A1TRPA1TSHR
SCHEMBL28826394 0.85 CYP3A4 (0.39) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL28053818 0.81 TRPA1 (0.52) CYP3A4ALDH1A1TRPA1HSD17B10SMN1; SMN2
SCHEMBL28053841 0.79 CYP3A4 (0.41) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL27948394 0.78 CYP3A4 (0.43) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL28053720 0.77 CYP3A4 (0.39) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL10676559 0.75 CYP3A4 (0.51) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL14587548 0.75 CYP3A4 (0.51) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL27579705 0.75 PKM (0.48) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL2879781 0.72 CYP3A4 (0.56) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN claimed
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN disclosed