SCHEMBL28053841

SCHEMBL28053841

C=CCOC(=O)C(C(=O)O)C(c1ccccc1)C(CC)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.40
ALDH1A1 P00352 6/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PKM P14618 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
OPRD1 P41143 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PDPK1 O15530 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
MME P08473 1/20 0.34
CASP1 P29466 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28053720 0.90 CYP3A4 (0.39) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL27948394 0.84 CYP3A4 (0.43) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL28826394 0.82 CYP3A4 (0.39) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL28053724 0.81 HKDC1 (0.47) ALDH1A1HSD17B10HKDC1MEN1KMT2A
SCHEMBL28053711 0.79 CYP3A4 (0.41) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL28053811 0.78 CYP3A4 (0.40) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL7212425 0.74 MMP8 (0.50) TSHRSMN1; SMN2HKDC1MEN1KMT2A
SCHEMBL10441680 0.73 PDPK1 (0.53) CYP3A4CYP2C19HSD17B10HKDC1MEN1
SCHEMBL10676559 0.72 CYP3A4 (0.51) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10
SCHEMBL5325702 0.72 CYP3A4 (0.51) CYP3A4CYP2C19ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN claimed
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN disclosed