Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20931741 | 0.87 | MEN1 (0.52) | SCN9AKCNH2SCN5AMAOAMAOB | |
| SCHEMBL25167089 | 0.82 | MEN1 (0.57) | SCN9AKCNH2SCN5AMAOBMEN1 | |
| SCHEMBL631841 | 0.81 | LOXL2 (0.62) | MAOAMAOBMEN1KMT2AKDM4E | |
| SCHEMBL28015509 | 0.81 | CCR1 (0.48) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL31616063 | 0.79 | MEN1 (0.66) | SCN9AKCNH2SCN5AMAOAMAOB | |
| SCHEMBL15055322 | 0.79 | RAB9A (0.62) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL28014896 | 0.79 | MEN1 (0.44) | SCN9AKCNH2SCN5AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL27760678 | 0.78 | ASIC3 (0.42) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL13452514 | 0.78 | LOXL2 (0.47) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL28748513 | 0.78 | SCN9A (0.48) | SCN9AKCNH2MAOBMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283443-A | Heterocyclic derivatives and use thereof | C & C RES LAB | 2016-01-27 | — | — | CN | disclosed |