Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053905 | 0.74 | GPR35 (0.40) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL28053872 | 0.69 | DAO (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL25409122 | 0.68 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL16557145 | 0.68 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL31435440 | 0.68 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL32686064 | 0.68 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL13977425 | 0.68 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL28949829 | 0.67 | NPC1 (0.40) | MEN1KMT2AALDH1A1PKMGPR35 | |
| SCHEMBL22777733 | 0.64 | BCL2L1 (0.46) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL16395791 | 0.64 | MEN1 (0.41) | MEN1KMT2AKDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283443-A | Heterocyclic derivatives and use thereof | C & C RES LAB | 2016-01-27 | — | — | CN | disclosed |