Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053905 | 0.77 | GPR35 (0.40) | BCL2L1GPR35DYRK1ACLK1DYRK1B | |
| SCHEMBL16395924 | 0.71 | BCL2L1 (0.47) | NPC1RAB9ASMN1; SMN2BCL2L1GPR35 | |
| SCHEMBL16395958 | 0.68 | BCL2L1 (0.47) | NPC1RAB9ASMN1; SMN2BCL2L1GPR35 | |
| SCHEMBL25260362 | 0.68 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2BCL2L1GPR35 | |
| SCHEMBL28053753 | 0.68 | DAO (0.36) | GPR35HPGDNFKB1LMNAALDH1A1 | |
| SCHEMBL28053949 | 0.67 | MEN1 (0.39) | NPC1RAB9ASMN1; SMN2BCL2L1GPR35 | |
| SCHEMBL25224046 | 0.65 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2BCL2L1GPR35 | |
| SCHEMBL31215720 | 0.64 | ALDH1A1 (0.44) | NPC1RAB9ASMN1; SMN2DYRK1ACLK1 | |
| SCHEMBL22777793 | 0.64 | DHODH (0.50) | NPC1RAB9ASMN1; SMN2BCL2L1NR1H4 | |
| SCHEMBL29448043 | 0.64 | DHODH (0.50) | NPC1RAB9ASMN1; SMN2BCL2L1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283443-A | Heterocyclic derivatives and use thereof | C & C RES LAB | 2016-01-27 | — | — | CN | disclosed |