Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25385324 | 0.91 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL24709495 | 0.87 | THRB (0.60) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL27485932 | 0.84 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL1047065 | 0.83 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL5070208 | 0.81 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL15901529 | 0.79 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28043245 | 0.79 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL17009099 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11693593 | 0.78 | THRB (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL21837192 | 0.78 | CHRNB2 (0.68) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849820-B | Resin-like material control agent and resin-like material control method | 播磨化成株式会社 | 2019-06-28 | — | — | CN | disclosed |
| CN-105273594-B | A kind of organic silicon polyurethane/urea anti-fouling material for being bonded the antifouling factor and preparation and application | 华南理工大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-106687118-A | Prodrug compounds and uses thereof | 配体药物公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-102540711-B | Color composition for color filter, color filter, display element and pigment dispersing liquid for colour filter | JSR株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-103031018-B | Water base ink for ink-jet recording group, water-based inks and ink jet recording method | BROTHER INDUSTRIES, LTD. (JP) | 2016-03-09 | — | — | CN | disclosed |