Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 3/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879625 | 0.86 | F2 (0.46) | ADAM17PREPFAPDPP4BLM | |
| SCHEMBL27879621 | 0.86 | F2 (0.46) | ADAM17PREPFAPDPP4BLM | |
| SCHEMBL27879658 | 0.79 | PREP (0.49) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL27896412 | 0.78 | ADAM17 (0.39) | ADAM17PREPFAPDPP4KDM4E | |
| SCHEMBL13570424 | 0.78 | VNN1 (0.50) | PREPFAPKDM4EBLMALOX15 | |
| SCHEMBL27879645 | 0.76 | SIGMAR1 (0.45) | PREPFAPDPP4DPP8DPP9 | |
| SCHEMBL27879607 | 0.74 | ADAM17 (0.41) | ADAM17SMN1; SMN2ALDH1A1 | |
| SCHEMBL27896558 | 0.74 | CYP3A4 (0.41) | ADAM17PREPFAPDPP4F2 | |
| SCHEMBL28797927 | 0.74 | KMT2A (0.45) | PREPFAPDPP4DPP8F2 | |
| SCHEMBL27879663 | 0.74 | ADAM17 (0.40) | ADAM17ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |