Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097509 | 0.86 | PBRM1 (0.88) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL203373 | 0.86 | PBRM1 (0.88) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29492473 | 0.86 | PBRM1 (0.88) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29363032 | 0.86 | PBRM1 (0.87) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL125621 | 0.86 | PBRM1 (0.87) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL9282073 | 0.86 | PBRM1 (0.87) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL147608 | 0.84 | PBRM1 (1.00) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29492479 | 0.84 | PBRM1 (0.83) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL9101086 | 0.84 | PBRM1 (0.83) | PBRM1NPC1MITFLMNAPOLB | |
| Hydrochloric Acid SCHEMBL8643223 | 0.84 | PBRM1 (0.83) | PBRM1NPC1MITFLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069918-B | Method for preparing 3-difluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2021-05-28 | — | — | CN | claimed |
| CN-108069918-A | Method for preparing 3-difluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2018-05-25 | — | — | CN | claimed |
| CN-107963996-A | Method for preparing 3-trifluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2018-04-27 | — | — | CN | claimed |
| CN-107963996-B | Method for preparing 3-trifluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-108069918-B | Method for preparing 3-difluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-105392838-B | Composition epoxy resin, prepreg and carbon fibre reinforced composite | 东丽株式会社 | 2018-12-14 | — | — | CN | disclosed |
| CN-108069918-A | Method for preparing 3-difluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-107963996-A | Method for preparing 3-trifluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2018-04-27 | — | — | CN | disclosed |
| CN-105392838-A | Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material | TORAY INDUSTRIES | 2016-03-09 | — | — | CN | disclosed |