Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28304781 | 0.86 | TSHR (0.40) | MEN1KMT2ARAB9APOLBL3MBTL1 | |
| SCHEMBL28055523 | 0.85 | KMT2A (0.44) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL28055480 | 0.85 | KMT2A (0.44) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL27825153 | 0.79 | PTGS2 (0.36) | MAPTRECQLTDP1TP53TSHR | |
| SCHEMBL28057650 | 0.76 | L3MBTL1 (0.46) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL27729027 | 0.75 | L3MBTL1 (0.49) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL27708790 | 0.72 | PDPK1 (0.44) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL28578731 | 0.72 | ALDH1A1 (0.40) | RAB9APOLBALDH1A1MAPTTDP1 | |
| SCHEMBL28686449 | 0.72 | MAPT (0.40) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL6913728 | 0.71 | ALDH1A1 (0.46) | MEN1KMT2ARAB9APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105439995-B | A kind of semicarbazone class compound and preparation method thereof, application | 西华大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-105348239-B | A kind of 1- (2- furyl) -3- (4- substituted-phenyl) acryloyl derivative and preparation method thereof, application | 西华大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-105439995-A | Semicarbazone compound and preparation method and application thereof | UNIV XIHUA | 2016-03-30 | — | — | CN | disclosed |
| CN-105348239-A | 1-(2-furyl)-3-(4-substituted phenyl)propylene derivative as well as preparation method and application thereof | UNIV XIHUA | 2016-02-24 | — | — | CN | disclosed |
| CN-105348233-A | 3-(2-furyl)propenol derivative as well as preparation method and application thereof | UNIV XIHUA | 2016-02-24 | — | — | CN | disclosed |