Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28304781 | 0.86 | TSHR (0.40) | KMT2AMEN1HPGDPOLBL3MBTL1 | |
| SCHEMBL28055528 | 0.85 | MEN1 (0.43) | KMT2AMEN1HPGDPOLBL3MBTL1 | |
| SCHEMBL28055523 | 0.85 | KMT2A (0.44) | KMT2AMEN1HPGDPOLBLMNA | |
| SCHEMBL27825153 | 0.79 | PTGS2 (0.36) | TDP1MAPTTP53TSHRKDM4E | |
| SCHEMBL28057650 | 0.76 | L3MBTL1 (0.46) | KMT2AMEN1HPGDPOLBL3MBTL1 | |
| SCHEMBL9508485 | 0.74 | MAOA (0.55) | KMT2AMEN1POLBL3MBTL1LMNA | |
| SCHEMBL9508489 | 0.74 | MAOA (0.55) | KMT2AMEN1POLBL3MBTL1LMNA | |
| SCHEMBL28053520 | 0.73 | POLB (0.43) | KMT2AMEN1HPGDPOLBLMNA | |
| SCHEMBL28578731 | 0.72 | ALDH1A1 (0.40) | HPGDPOLBTDP1MAPTALDH1A1 | |
| SCHEMBL27339159 | 0.72 | TRPA1 (0.45) | KMT2AMEN1HPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348239-B | A kind of 1- (2- furyl) -3- (4- substituted-phenyl) acryloyl derivative and preparation method thereof, application | 西华大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-105439995-B | A kind of semicarbazone class compound and preparation method thereof, application | 西华大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-105439995-A | Semicarbazone compound and preparation method and application thereof | UNIV XIHUA | 2016-03-30 | — | — | CN | disclosed |
| CN-105348239-A | 1-(2-furyl)-3-(4-substituted phenyl)propylene derivative as well as preparation method and application thereof | UNIV XIHUA | 2016-02-24 | — | — | CN | disclosed |
| CN-105348233-A | 3-(2-furyl)propenol derivative as well as preparation method and application thereof | UNIV XIHUA | 2016-02-24 | — | — | CN | disclosed |